Can Seroquel cause depression?

  • Yes.

    Following is a response initially composed for a similar question, found here: Mark Dunn’s answer to Can olanzapine cause anxiety? considering that all antipsychotics include the exact same basic neuropsychological risks and can all cause depression and experiences which resemble depression even if the drug results themselves are not all related beyond all being caused by the exact same drug.

    I. Antipsychotic Risks

    Antipsychotics are infamous for their unfavorable neuropsychological results, which are extremely typical and frequently rather popular. Amongst these results, brand-new or getting worse anxiety is an issue, along with concerns such as anxiety or panic attacks, amotivation, anhedonia, psychosis, mania, insomnia, cognitive problems, amnesia, and so forth. Why somebody is taking an antipsychotic does not identify or limit what side effects may happen, and everyone responds uniquely to brain-altering drugs. Your asking the concern “Can?” is hence most proper, as we can not anticipate exactly who will experience what and no two people will necessarily have the very same experience even if they utilize the same drug and dose for the very same length of time.

    Neuropsychological drug impacts– and non-psychological dysfunctions which can lead to or additional them (for example through drug-induced nutritional shortages)– can possibly last well beyond the time in which somebody is using an antipsychotic. Not just can drug impacts continue beyond one’s dosing period, but brand-new or more extreme negative effects can develop as someone attempts to give up or recuperate from utilizing an antipsychotic. This is partially due to concerns like physical dependence and neuroplastic reactions to intrusive, dysfunction-creating drugs, though outright damages are often a problem also. Antipsychotics, putting things directly, are chemical lobotomies

    That said, it might be difficult or made complex to distinguish collections of side effects from a combined ‘episode’ of depression secondary to antipsychotic use. “Anxiety” describes psychosocial experiences (mindsets, feeling, acting), but implies a specific type of relationship in between the experiences fulfilling whatever diagnostic requirements we are utilizing. Since the requirements themselves do not refer to what is causing the experiences, and the experiences are mostly determined for without assigning cause, we can have a hard time to determine a label when the extremely exact same experiences can be “anxiety” or be something else which occurs to look the very same psychosocially.

    Things like anhedonia, amotivation, passiveness, difficulty sleeping or falling asleep, hypersomnia (sleeping a ton), trouble believing, focusing, and interacting, social withdrawal, physical fatigue or sleepiness, modifications in consuming routines, sexual dysfunction, and other common or very common impacts of antipsychotics can be indistinguishable from “anxiety” as a specific procedure with a combined cause. We assign labels based upon experiences rather than a physical or unbiased distinction between one state and another. The point at which a group of potentially unrelated drug effects ends up being “depression” instead of just a lot of impacts which look like depression is somewhat arbitrary.

    II. Defining Depression

    There are 3 kinds of depression we should know:

    • Anxiety as a sign of a medical problem
    • Anxiety that is not a symptom of a medical problem
    • Depression which neither receives medical nor psychiatric labeling

    Drug effects are the first type of depression, whereas ideas like “major depressive disorder” are the 2nd kind. All psychiatric diagnoses require that we are discussing experiences that are not originating from drug effects or medical issues. This means that an antipsychotic causing depression or parts of anxiety omits the possibility of utilizing any psychiatric medical diagnosis to label what someone is going through. This gets difficult since lots of medical professionals will misdiagnose the neuropsychological effects of psychiatric drugs as being “mental illness” instead of the medical problems they in fact are.

    Though perhaps the difference seems like common sense in most cases, a lot of medical professionals operate under the assumption that discontinuation of the antipsychotic will dependably solve any adverse impacts. There is also an extremely limited professional understanding of how stopping an antipsychotic can trigger new or magnified drug results, like withdrawal and rebound phenomena, tardive results which only emerge after drug discontinuation, and tension syndromes arising from the strain of attempting to get used to the absence of a drug someone has actually become dependent upon– frequently following many months or perhaps years of use.

    These sort of problems can take a very long time to fix, months or years for a lot of patients, and numerous doctors will claim they are “mental illness” since they do not or won’t acknowledge comprehend the profoundness of the changes and interruptions brought on by antipsychotic use, especially continuous usage. Because the service is almost undoubtedly to return to utilizing drugs, which can often peaceful down a few of the withdrawal and rebound symptoms, the really circumstance of being physically dependent upon a drug is mentioned as in fact demonstrating that somebody requires drug use due to the fact that their brain was ‘broken’ before drugs ever entered the picture. It is a tricky and deceitful argument, however it keeps many patients returning.

    III. Reacting To Drug Results

    Regardless, experiences or symptoms that are recognizable as “anxiety” or being really comparable to depression warrant serious and instant address. What this appears like depends on the situation and on the particular individual, but physical work-ups and professional consultation might be useful and the prescriber or prescribers of all drugs should be informed and involved to some level in any differential diagnosing. Antipsychotics cause a lot of unusual things to take place that we simply do not understand, and experiences like depression are already beyond our understanding considered that the brain itself is largely a mystery to modern science.

    This highlights the need to concentrate on recovery rather than labels– if something appears to be making your circumstance worse, that is the most appropriate factor to discuss. How to examine the risks and options is likewise important, however knowing that you don’t like the instructions things have taken and wish to change course is a fundamental assessment that does not need expensive medical diagnoses or discussing how specific drugs or drug interactions are causing your experiences. That lots of parties within the industry, including a lot of prescribers, play dirty does indicate that patients need to proactively safeguard themselves versus mismanagement and misdiagnosing.

    To increase your understanding of antipsychotics, I share a couple of preliminary sources below talking about key facts to know about antipsychotics before or throughout usage, and basic background about how antipsychotic dangers, utilizes, and management. One is a Quora answer of mine, the rest are psychiatrist-written guides. Such resources can be part of developing a more useful framework in which to engage with psychiatry and drug usage, I motivate everybody to continue broadening their details bases and to not take any claims at face value (even if they come from people with credentials or citations of published studies and the like).

    Psychotropic drugging is a largely undiscovered and badly understood expanse and popular theories change week to week. What gets a single person where they want to be going may be quite various from what another person finds ideal, and commercial systemization of beliefs and practices frequently sacrifice the wellbeing of individual patients for the convenience and financial benefits of acting like all of us have really comparable needs, goals, and priorities. Finding out more can empower our capability to make constructive healthcare choices and to critically assess the options and declarations that other people give the table. Awareness is essential, and can account for just how much we don’t referred to as well as what we might.

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